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GRADE methodology to evaluate evidence quality and determine the strength of each recommendation Primarily aimed at WHO announces development of updated guidelines for the psychosocially assisted pharmacological treatment of opioid dependence and community management of opioid overdoseIn 2022, approximately 60 million people globally engaged in non-medical opioid use, including the use of drugs like heroin, morphine, codeine, fentanyl, methadone, tramadol, and other similar substances Their regular non Drug-resistant TB continues to pose a serious threat, with 150 000 new cases estimated in 2024 The Region has reduced TB incidence by 16% since 2015, slightly faster than the global average of 12% But deaths are not falling fast enough, and the Region’s TB incidence rate of 201 per 100 000 people – remains well above the global average of --- who int 14-07-2025-who-recommends-injectable-lenacapavir-for-hiv-prev The use of psychoactive drugs without medical supervision is associated with significant health risks and can lead to the development of drug use disorders Drug use disorders, particularly when untreated, increase morbidity and mortality risks for individuals, can trigger substantial suffering and lead to impairment in personal, family, social, educational, occupational or other important --- who int health-topics drugs-psychoactive About WHO Drug Information WHO Drug Information is a quarterly journal providing an overview of topics relating to medicines development and regulation which is targeted to a wide audience of health professionals and policy makers Launched in 1987, WHO Drug Information communicates the latest international news and trends to regulatory agencies, academic and training institutions, researchers --- who int 17-05-2024-who-updates-list-of-drug-resistant-bacteria-most-t --- who int tools atc-ddd-toolkit atc-classification--- who int health-topics medicinesAbout WHO Drug Information WHO Drug Information is a quarterly journal providing an overview of topics relating to medicines development and regulation which is targeted to a wide audience of health professionals and policy makers Launched in 1987, WHO Drug Information communicates the latest international news and trends to regulatory agencies, academic and training institutions, researchers 6 days ago · Drug -resistant TB continues to pose a serious threat, with 150 000 new cases estimated in 2024 The Region has reduced TB incidence by 16% since 2015, slightly faster than the global average of 12% But deaths are not falling fast enough, and the Region’s TB incidence rate of 201 per 100 000 people – remains well above the global average of --- who int teams mental-health-and-substance-use drugs-psychoactive--- who int 09-02-2025-who-updates-guidelines-on-opioid-dependence-treatm Module 4: treatment and care encompass all current recommendations for managing drug-susceptible and drug-resistant TB, alongside patient care and support strategies Developed according to 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